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Top Covid experts on the questions they want answered about Omicron

by Enochadmin

For some Covid consultants, what’s most unsettling concerning the Omicron variant is all of the uncertainty surrounding it. That’s what retains John Moore, a professor of microbiology and immunology at Weill Cornell Medical School, up at evening.

“I’ve misplaced extra sleep worrying about answering questions on Omicron than over Omicron itself,” he stated throughout a panel at STAT’s “A Look Forward at Biotech 2022”occasion final week.

Moore, like many different consultants, is ready for extra information earlier than judging how the brand new variant goes to pan out. Extra time will inform us whether or not Omicron will fizzle out and be forgettable like Beta, or if it is going to be far more consequential and exchange Delta, in a lot the identical approach Delta changed Alpha.


“If we begin to see lots of vaccinated individuals within the hospitals with Omicron, that’s going to be one thing that modifications the face of the pandemic within the USA,” he stated. “That’s not occurred but.”

However, he added, it’s not clear but whether or not that’s as a result of too little time has handed for the variant’s true impression to be revealed, or whether it is as a result of that worst-case state of affairs shouldn’t be going to occur.


One other Omicron unknown is the share of Covid circumstances within the U.S. that contain the brand new variant. The small clusters seen to this point don’t inform consultants sufficient, he stated. Unhappy with the dearth of data, epidemiologists and infectious illness physicians are rising impatient — as is the general public, which is clamoring for insights.

“We’re so thirsty for information now and due to this fact we’re reaching for something,” Wafaa El-Sadr, founder and director of the Worldwide Middle for AIDS Care and Remedy Program at Columbia College, stated on the panel. She pointed to a latest 12-person research on Omicron that supplied a really early have a look at the variant.

From left, Matthew Herper, Céline Gounder, Wafaa El-Sadr, and John Moore talk about the Covid-19 pandemic at a panel in December 2021.

“You’ll be able to see lots of unusual issues in 12 individuals, and also you’ve acquired to be very cautious with what you generalize, El-Sadr stated. She additionally cautioned towards placing an excessive amount of forex in anecdotes coming from the bottom in South Africa and the U.Ok. “We’re all greedy at these little hints right here and there, and that, I feel, is kind of unsettling.”

El-Sadr is assured that scientists will discover extra sturdy information within the coming weeks. These findings, she stated, will present perception into how infectious the variant is, how lethal it’s and most significantly whether or not it might be capable to “outsmart” present vaccinations and coverings.

Proper now, Moore stated, the world remains to be in a section of not having “sufficient info to know what’s going to occur.”

“There’s nonetheless so much that we don’t have solutions to but,” stated Céline Gounder, an infectious illness specialist and epidemiologist at NYU and Bellevue Hospital. “It does seem like very infectious, doubtless much more infectious than Delta.”

Delta, she stated, was so lethal as a result of it was so infectious. “If that’s the case many individuals get contaminated, even when it’s a much less virulent variant — which we nonetheless don’t have a solution on with Omicron— it might probably nonetheless be very lethal,” stated Gounder.

“That’s truly what I’m most involved about within the second about Omicron,” she stated.

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